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HomeHealth EducationCan Your Bones Profit from Omega-3s?

Can Your Bones Profit from Omega-3s?

By Dr. Susan Brown and Cameron Vazquez, MPH

You’ve heard of omega-3s for mind well being and coronary heart well being, however have you ever heard about omega-3s for bone well being? Given the myriad advantages these essential anti-inflammatory vitamins have on our well being, it was solely pure to discover whether or not these advantages lengthen to bone. And certainly, they do. Omega-3 fatty acids have been proven to cut back fracture danger and reduce bone loss, making them one other key nutrient to assist bone well being.

Omega-3s and Fracture Danger

Quite a few research assert that omega-3s straight affect fracture danger normally and danger of hip fracture particularly.

A 2015 research (1) discovered that males who had the best ranges of polyunsaturated fatty acids (PUFAs), omega-3s, and EPA had the bottom danger of basic fracture in comparison with males with the bottom ranges of PUFAs, omega-3s, and EPA. The ladies on this research skilled a decrease danger of basic fracture after they had greater ranges of PUFAs.

This research additionally discovered that every day fish oil consumption, a substance with excessive concentrations of omega-3s, throughout midlife diminished a lady’s fracture danger by 25% and a person’s fracture danger in late life by 36%.

One other research inspecting postmenopausal girls discovered an analogous pattern when taking a look at hip fracture. The truth is, the research asserts that the quantity of α-linolenic acid (ALA), eicosapentaenoic acid (EPA), and complete omega-3 polyunsaturated acids (PUFAs) in purple blood cells is a serious predictor of hip fracture. Greater ranges of omega-3 fat had been related to a decrease danger for fracture. (2)

Omega-6/Omega-3 Ratio and Fracture Danger

Many research cite excessive ranges of PUFAs as protecting towards bone. This consists of each omega-6 PUFAs and omega-3 PUFAs. Nevertheless, analysis has discovered that there’s significance within the ratio of omega-6 PUFAs to omega-3 PUFAs. As an illustration, a research inspecting postmenopausal girls discovered {that a} greater omega-6/omega-3 ratio predicts a better danger for hip fracture. The truth is, the individuals with the best n-6/n-3 suffered from double the hip fractures. (2)

It is sensible {that a} excessive omega-6 to omega-3 ratio would enhance the danger of hip fracture. It’s well-known that having too many omega-6s in comparison with omega-3s contributes to quite a lot of critical inflammatory illnesses resembling coronary heart illness, most cancers, and autoimmune problems. (3)

Omega-3s and Bone Mineral Density

Not solely does knowledge assist that omega-3s dramatically cut back fracture danger, but in addition the analysis means that omega-3s straight influence bone mineral density. That is achieved by facilitating bone mineralization, lowering irritation, and defending towards extreme bone breakdown. (4)

Bone mineral loss is the results of an imbalance between bone formation by osteoblast cells and bone resorption by osteoclast cells. Omega-3s can enhance bone-building cell exercise and cut back the exercise of bone breakdown cells. One research even instructed that 4.5 to six grams per day of EPA and DHA can have healing results on bone loss. (5)

Not solely have the bone advantages of omega-3s been replicated in populations all around the world, together with in South Korea (6), China (7), Spain (8), and Iceland (1), however they’ve additionally been seen in research performed by NASA on astronauts who’ve lived past our world. Astronauts lose bone due to the weightlessness they expertise in house journey. On common, astronauts lose 1 to 1.5% of bone per 30 days whereas dwelling in house. (9)

To fight this bone loss, researchers investigated the results of omega-3s and located that astronauts who consumed extra fish (and due to this fact extra omega-3s) suffered much less bone loss following their return from 4- to 6-month house flights. (10)

Omega-3s and Steroid-Induced Osteoporosis

Glucocorticoids resembling prednisone, are the principle reason behind secondary osteoporosis and osteoporosis earlier than the age of fifty. (11)

Lowering the harm to the bone from steroid drugs is essential and a current Russian research means that omega-3 fat may help. Though this was an animal research, it demonstrated that omega-3 fat can stop bone loss from steroid use. That is more than likely as a result of anti-inflammatory actions of omega-3 fat. (12)

We sit up for extra human research, in addition to newer and extra modern research sooner or later to substantiate these findings.

Higher Your Bones with Omega-3s

Right here on the Heart for Higher Bones, omega-3 fat rank amongst the vital bone-building vitamins, as does the ratio of omega-6s to omega-3s. Now, with breakthrough know-how, it’s potential with a easy at-home blood spot check to get a complete evaluation to measure each your omega-3 fat and your omega-6 to omega-3 ratio, and to detect when you have poisonous trans fat.Omega 3 Master class

Click on for References


  1. Harris, T. B., et al. 2015. Plasma phospholipid fatty acids and fish-oil consumption in relation to osteoporotic fracture danger in older adults: The Age, Gene/Surroundings Susceptibility Examine. American Journal of Medical Diet 101(5):947-955.
  2. Orchard, T. S., et al. 2013. The affiliation of purple blood cell n-3 and n-6 fatty acids with bone mineral density and hip fracture danger within the girls’s well being initiative. Journal of Bone and Mineral Analysis 28(3):505-515.
  3. Simopoulos, A. P. 2006. Evolutionary facets of eating regimen, the omega-6/omega-3 ratio and genetic variation: Dietary implications for power illnesses. Biomedicine & Pharmacotherapy 60(9):502-507.
  4. Sharma, T. and C. C. Mandal. 2020. Omega-3 fatty acids in pathological calcification and bone well being. Journal of Meals Biochemistry 44(8):e13333.
  5. Fazelnia, F. and N. Khodabandehloo. 2019. Preventive and healing impact of omega-3 supplementation on bone mineral density in folks aged 60 years and older: A scientific assessment. Inside Drugs and Medical Investigation Journal 4(1):9-15.
  6. Moon, H.-J., et al. 2012. Constructive correlation between erythrocyte ranges of n-3 polyunsaturated fatty acids and bone mass in postmenopausal Korean girls with osteoporosis. Annals of Diet and Metabolism 60(2):146-153.
  7. Chen, Y. M., et al. 2010. Greater sea fish consumption is related to higher bone mass and decrease osteoporosis danger in postmenopausal Chinese language girls. Osteoporosis Worldwide 21:939-946.
  8. Lavado-García, J., et al. 2018. Lengthy-chain omega-3 polyunsaturated fatty acid dietary consumption is positively related to bone mineral density in regular and osteopenic Spanish girls. PLoS ONE 13(1):e0190539.
  9. Stavnichuk, M., et al. 2020. A scientific assessment and meta-analysis of bone loss in house vacationers. Npj Microgravity 6:article 13.
  10. NASA (Nationwide Aeronautics and House Administration). 2010. NASA research discover omega-3 might assist cut back bone loss. Science Day by day 11 Might 2010.
  11. Briot, Okay. and C. Roux. 2015. Glucocorticoid-induced osteoporosis. RMD Open 1(1):e000014.
  12. Elbahnasawy, A. S., et al. 2019. Protecting impact of dietary oils containing omega-3 fatty acids towards glucocorticoid-induced osteoporosis. Journal of Diet and Well being 52(4):323-331.



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