Deep eutectic solvents (DESs) have been used for the primary time as a sustainable medium in a ruthenium-catalyzed C-H activation response. This research describes an environment friendly, easy and straightfoward protocol for the direct C-H activation of a broad vary of fragrant substrates and response with a number of olefins and alkynes, affording effectively attention-grabbing heterocyclic methods as merchandise. A easy, strong and commercially accessible ruthenium catalyst was used together with completely different DESs underneath completely different response circumstances. This system was appropriate with the usage of both inner or exterior oxidant (oxygen from air) utilizing a catalytical quantity of copper salts for the final case. Completely different purposeful directing teams had been properly tolerated acquiring promising outcomes, that had been comparable and even higher that these reported in literature. Additionally, the response medium may very well be recycled as much as 3 consecutive instances and this transformation may very well be carried out on a gram scale with wonderful yield